Pub. Date : 2007 Apr
PMID : 17491508
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In human liver the presence of LCA is sensed by the pregnane X receptor (PXR) which has the potential to switch on all the genes required for safe metabolism and elimination of LCA from the body. | Lithocholic Acid | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 2 | In human liver the presence of LCA is sensed by the pregnane X receptor (PXR) which has the potential to switch on all the genes required for safe metabolism and elimination of LCA from the body. | Lithocholic Acid | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 3 | In human liver the presence of LCA is sensed by the pregnane X receptor (PXR) which has the potential to switch on all the genes required for safe metabolism and elimination of LCA from the body. | Lithocholic Acid | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 4 | In human liver the presence of LCA is sensed by the pregnane X receptor (PXR) which has the potential to switch on all the genes required for safe metabolism and elimination of LCA from the body. | Lithocholic Acid | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 5 | Similarly, PXR exposure to LCA produces up-regulated expression of the membrane transporters MDR1 and MRP2 which excrete metabolites of LCA. | Lithocholic Acid | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 6 | Similarly, PXR exposure to LCA produces up-regulated expression of the membrane transporters MDR1 and MRP2 which excrete metabolites of LCA. | Lithocholic Acid | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |