Title : Critical role for D-type cyclins in cellular transformation induced by E6/E7 of human papillomavirus type 16 and E6/E7/ErbB-2 cooperation.

Pub. Date : 2007 Jul

PMID : 17489986






2 Functional Relationships(s)
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1 We confirm that NEF-E6/E7 and NEF-E6/E7/ErbB-2, but not NEF-ErbB-2 cells, induce colony formation in soft agar and tumor formation in nude mice. Agar erb-b2 receptor tyrosine kinase 2 Mus musculus
2 Nevertheless, D3(-/-)E6/E7/ErbB-2 cells resulted in up to a 60 and 50% decrease in colony and tumor formation in soft agar and nude mice, respectively, compared with NEF-E6/E7/ErbB-2 cells. Agar erb-b2 receptor tyrosine kinase 2 Mus musculus