Pub. Date : 2007 May
PMID : 17488862
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Cocaine is a sympathomimetic agent that can cause coronary artery vasospasm leading to myocardial ischaemia, acute coronary syndrome and acute myocardial infarction (ACS/AMI). | Cocaine | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) | Homo sapiens |
| 2 | The management of cocaine-induced ACS/AMI is different to classical atheromatous ACS/MI, because the mechanisms are different. | Cocaine | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) | Homo sapiens |
| 3 | Retrospective study--Cocaine use or non-use was documented in 3.7% (4/109) and 4% (2/50) of clinical notes of patients with suspected and proven ACS, respectively. | Cocaine | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) | Homo sapiens |
| 4 | DISCUSSION: Although junior medical staff are aware that cocaine is a risk factor for ACS/AMI, they are less likely to ask about it in routine clinical practice or record its use/non-use in clinical notes. | Cocaine | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) | Homo sapiens |
| 5 | It is essential that patients presenting with suspected ACS are asked about cocaine use, since the management of these patients is different to those with ACS secondary to "classical" cardiovascular risk factors. | Cocaine | 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) | Homo sapiens |