Title : 7,8-Dihydroxy-4-methylcoumarin induces apoptosis of human lung adenocarcinoma cells by ROS-independent mitochondrial pathway through partial inhibition of ERK/MAPK signaling.

Pub. Date : 2007 May 29

PMID : 17485089






1 Functional Relationships(s)
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1 In addition, our immunoblot data revealed that DHMC treatment led to down-regulation of Bcl-xl, Bax, p21, Cox-2, p53 and upregulation of c-Myc. 7,8-dihydroxy-4-methylcoumarin MYC proto-oncogene, bHLH transcription factor Homo sapiens