Title : Drug-drug interactions in the metabolism of imidafenacin: role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes.

Pub. Date : 2007 Feb

PMID : 17484517






1 Functional Relationships(s)
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1 Clinically established CYP3A4 inhibitors including itraconazole, ketoconazole, erythromycin and clarithromycin inhibited the elimination of IM in HLM. Itraconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens