Pub. Date : 2007 Sep
PMID : 17475919
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inherent AChE-R overproduction under organophosphate intoxication confers both short-term protection (as a bioscavenger) and long-term neuromuscular damages (as a regulator). | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | AChE-R(ER) purified to homogeneity showed indistinguishable biochemical properties, with IC50 = 10(-7) M for the organophosphate paraoxon, similar to mammalian cell culture-derived AChE. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | Our findings present plant-produced AChE-R(ER) as a bimodal agent, conferring both short- and long-term protection from organophosphate intoxication. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |