Pub. Date : 2007 Jun 1
PMID : 17467021
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Glutathione regulation of redox-sensitive signals in tumor necrosis factor-alpha-induced vascular endothelial dysfunction. | Glutathione | tumor necrosis factor | Homo sapiens |
2 | We investigated the regulatory role of glutathione in tumor necrosis factor-alpha (TNF-alpha)-induced vascular endothelial dysfunction as evaluated by using vascular endothelial adhesion molecule expression and monocyte-endothelial monolayer binding. | Glutathione | tumor necrosis factor | Homo sapiens |
3 | We investigated the regulatory role of glutathione in tumor necrosis factor-alpha (TNF-alpha)-induced vascular endothelial dysfunction as evaluated by using vascular endothelial adhesion molecule expression and monocyte-endothelial monolayer binding. | Glutathione | tumor necrosis factor | Homo sapiens |
4 | Inhibition of glutathione synthesis by l-buthionine-(S,R)-sulfoximine (BSO) resulted in down-regulations of the TNF-alpha-induced adhesion molecule expression and monocyte-endothelial monolayer binding. | Glutathione | tumor necrosis factor | Homo sapiens |
5 | Our study indicates that TNF-alpha induces adhesion molecule expression and monocyte-endothelial monolayer binding mainly via activation of NF-kappaB in a glutathione-sensitive manner. | Glutathione | tumor necrosis factor | Homo sapiens |