Pub. Date : 2007 Apr 30
PMID : 17464175
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin is a polyphenolic compound possessing interesting anti-inflammatory and antioxidant properties and has the ability to induce the defensive protein heme oxygenase-1 (HO-1). | Curcumin | heme oxygenase 1 | Homo sapiens |
| 2 | Curcumin is a polyphenolic compound possessing interesting anti-inflammatory and antioxidant properties and has the ability to induce the defensive protein heme oxygenase-1 (HO-1). | Curcumin | heme oxygenase 1 | Homo sapiens |
| 3 | In additional experiments, an inhibitor of heme oxygenase activity (tin protoporphyrin IX, 10 microM) or siRNA for HO-1 were used to investigate the participation of HO-1 as a mediator of curcumin-induced effects. | Curcumin | heme oxygenase 1 | Homo sapiens |
| 4 | Treatment with curcumin produced a marked induction of cardiac HO-1 in normothermic condition but cells were less responsive to the polyphenolic compound at low temperature. | Curcumin | heme oxygenase 1 | Homo sapiens |
| 5 | Thus, curcumin added to Celsior preservation solution effectively prevents the damage caused by cold-storage; this effect involves the protective enzyme HO-1 but also other not yet identified mechanisms. | Curcumin | heme oxygenase 1 | Homo sapiens |