Title : Inhibition of ERK1/2 activation by phenolic antioxidants protects kidney tubular cells during cold storage.

Pub. Date : 2007 Apr 15

PMID : 17460567






1 Functional Relationships(s)
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1 CONCLUSION: The results suggest that chilling of renal epithelial cells induces ROS generation by NADPH oxidase, which leads to rapid activation of the MEK-ERK1/2 cascade and initiation of cell injury. Reactive Oxygen Species mitogen-activated protein kinase 3 Homo sapiens