Pub. Date : 2007 Jun
PMID : 17458858
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan. | Zymosan | interleukin 10 | Mus musculus |
2 | Zymosan is a particulate yeast preparation that elicits high levels of IL-2 and IL-10 from dendritic cells (DC) and engages multiple innate receptors, including the Syk-coupled receptor dectin-1 and the MyD88-coupled receptor TLR2. | Zymosan | interleukin 10 | Mus musculus |
3 | Here, we show that induction of IL-2 and IL-10 by zymosan requires activation of ERK MAP kinase in murine DC. | Zymosan | interleukin 10 | Mus musculus |