Title : Selective COX-2 inhibitor versus indomethacin for the prevention of heterotopic ossification after hip replacement: a double-blind randomized trial of 100 patients with 1-year follow-up.

Pub. Date : 2007 Feb

PMID : 17453399






2 Functional Relationships(s)
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1 METHODS: We performed a randomized controlled study to evaluate the effect of the selective COX-2 inhibitor rofecoxib compared to that of indomethacin on the incidence and extent of heterotopic ossification in patients who had undergone hip replacement surgery. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 INTERPRETATION: After short-term administration, the selective COX-2 inhibitor rofecoxib was effective in preventing heterotopic ossification after total hip arthroplasty. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens