Title : Structures of vaccinia virus dUTPase and its nucleotide complexes.

Pub. Date : 2007 May

PMID : 17452782






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate in the presence of Mg(2+) ions. 2'-deoxyuridylic acid Deoxyuridine triphosphatase Drosophila melanogaster
2 The crystal structure of vaccinia virus dUTPase has been solved and the active site has been mapped by crystallographic analysis of the apo enzyme and of complexes with the substrate-analog dUMPNPP, with the product dUMP and with dUDP, which acts as an inhibitor. 2'-deoxyuridylic acid Deoxyuridine triphosphatase Drosophila melanogaster