Title : Congenital hyperinsulinism in an infant caused by a macroscopic insulin-producing lesion.

Pub. Date : 2007 Mar

PMID : 17451083






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Severe congenital hyperinsulinism is most often due to inactivating mutations in either the ABCC8 or KCNJ11 genes, which encode the SUR1 and Kir6.2 proteins, respectively--the two components of the ATP-sensitive K+ (KATP) channel; neonatal hypoglycemia due to macroscopic insulin-producing pancreatic lesions or adenomas are extremely rare. Adenosine Triphosphate ATP binding cassette subfamily C member 8 Homo sapiens
2 Severe congenital hyperinsulinism is most often due to inactivating mutations in either the ABCC8 or KCNJ11 genes, which encode the SUR1 and Kir6.2 proteins, respectively--the two components of the ATP-sensitive K+ (KATP) channel; neonatal hypoglycemia due to macroscopic insulin-producing pancreatic lesions or adenomas are extremely rare. Adenosine Triphosphate ATP binding cassette subfamily C member 8 Homo sapiens