Title : The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia.

Pub. Date : 2007 Mar

PMID : 17446490






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we report that the three isoforms show similar activity evaluated as [Ca2+]i increase evoked by Na+-free medium exposure in Fura-2-loaded single cells and NCX3 transfected cells are less vulnerable to chemical hypoxia compared to NCX1- and NCX2-transfected cells, suggesting that NCX3 could play a more relevant protective role during chemical hypoxia. Fura-2 solute carrier family 8 member A1 Homo sapiens