Title : Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species.

Pub. Date : 2007 Jun 30

PMID : 17445780






1 Functional Relationships(s)
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1 In contrast, exposure of cells to the specific proteasome inhibitors: epoxomicin (1-5 microM), proteasome inhibitor I (5-10 microM) or lactacystin (5-15 microM) completely inhibited TCDD-induced degradation of the AHR. epoxomicin aryl hydrocarbon receptor Homo sapiens