Pub. Date : 2006 Dec
PMID : 17438698
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Compared with scald group, the level of IRS-1 Serine307 phosphorylation and JNK activity in scald and SP600125 group were decreased but tyrosine phosphorylation was elevated. | pyrazolanthrone | insulin receptor substrate 1 | Rattus norvegicus |
| 2 | CONCLUSION: SP600125 can partially ameliorate insulin resistance after scald by inhibition of JNK activation, and decrease the level of IRS-1 phospho-serine307. | pyrazolanthrone | insulin receptor substrate 1 | Rattus norvegicus |