Title : Impact of trivalent arsenicals on selenoprotein synthesis.

Pub. Date : 2007 Mar

PMID : 17431482






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Monomethylarsonous acid (MMA(III)) treatment of cells, in contrast, did not block all new synthesis of selenoproteins but did result in an increase in cytosolic thioredoxin reductase (TrxR1) at both the mRNA and protein levels. monomethylarsonous acid thioredoxin reductase 1 Homo sapiens
2 CONCLUSIONS: These results suggest that arsenite and MMA(III) are key metabolites that trigger higher levels of TrxR1, and both lead to a reduction in the expression of cGpx. monomethylarsonous acid thioredoxin reductase 1 Homo sapiens