Pub. Date : 2007 Nov 1
PMID : 17425515
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1. | Lysine | beta-secretase 1 | Homo sapiens |
| 2 | In the present study we report that BACE1 is acetylated on seven lysine residues of the N-terminal portion of the nascent protein. | Lysine | beta-secretase 1 | Homo sapiens |
| 3 | Site-directed mutagenesis indicates that lysine acetylation is necessary for nascent BACE1 to leave the ER and move ahead in the secretory pathway, and for the molecular stabilization of the protein. | Lysine | beta-secretase 1 | Homo sapiens |