Title : Induction of drug resistance and transformation in human cancer cells by the noncoding RNA CUDR.

Pub. Date : 2007 Jun

PMID : 17416635






2 Functional Relationships(s)
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1 By using the technique of RT-PCR-based differential display, a novel gene, cancer up-regulated drug resistant (CUDR) gene, was found to be overexpressed in a doxorubicin-resistant subline of human squamous carcinoma A431 and A10A cells, which were also more resistant to drug-induced apoptosis. Doxorubicin urothelial cancer associated 1 Homo sapiens
2 Stable transfection with the CUDR gene was found to induce resistance to doxorubicin and etoposide as well as drug-induced apoptosis in A431 cells. Doxorubicin urothelial cancer associated 1 Homo sapiens