Title : Knockdown of ACAT-1 reduces amyloidogenic processing of APP.

Pub. Date : 2007 Apr 17

PMID : 17412327






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Previous studies have shown that acyl-coenzyme A:cholesterol acyl transferase (ACAT), an enzyme that controls cellular equilibrium between free cholesterol and cholesteryl esters, modulates proteolytic processing of APP in cell-based and animal models of Alzheimer"s disease. Cholesterol Esters carboxylesterase 1 Homo sapiens