Title : Design, synthesis, and evaluation of tripeptidic promoieties targeting the intestinal peptide transporter hPEPT1.

Pub. Date : 2007 Apr

PMID : 17407174






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The affinity of the tripeptides to hPEPT1 was determined by measuring the inhibition of [(14)C]Gly-Sar in mature Caco-2 cell monolayers which resulted in K(i) values ranging from 0.22 to 25 mM or above. Glycine solute carrier family 15 member 1 Homo sapiens
2 Translocation through the intestinal membrane, mediated by hPEPT1, was measured by recording the membrane potential relative to that induced by the known substrate Gly-Sar. Glycine solute carrier family 15 member 1 Homo sapiens