Title : A role for cyclooxygenase in aging-related changes of beta-adrenoceptor-mediated relaxation in rat aortas.

Pub. Date : 2007 Jun

PMID : 17404710






1 Functional Relationships(s)
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1 The age-related increase in COX-1 and COX-2 protein led to elevation of prostacyclin (measured as 6-keto prostaglandin F(1alpha)) and thromboxane A(2) (measured as thromboxane B(2)) in 54-week compared to 8-week-old aortas. Epoprostenol cytochrome c oxidase II, mitochondrial Rattus norvegicus