Pub. Date : 2007 May 15
PMID : 17386920
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Assay of angiotensin I-converting enzyme-inhibiting activity based on the detection of 3-hydroxybutyric acid. | 3-Hydroxybutyric Acid | angiotensin I converting enzyme | Homo sapiens |
| 2 | Under the actions of ACE and aminoacylase, 3HB-GGG is cleaved into amino acids (Gly and Gly-Gly) and 3-hydroxybutyric acid (3HB). | 3-Hydroxybutyric Acid | angiotensin I converting enzyme | Homo sapiens |
| 3 | Under the actions of ACE and aminoacylase, 3HB-GGG is cleaved into amino acids (Gly and Gly-Gly) and 3-hydroxybutyric acid (3HB). | 3-Hydroxybutyric Acid | angiotensin I converting enzyme | Homo sapiens |
| 4 | The assay conditions were optimized and applied to monitor the ACE inhibitory activity in terms of 3HB measured using an F-kit. | 3-Hydroxybutyric Acid | angiotensin I converting enzyme | Homo sapiens |
| 5 | Under the optimum assay parameters-ACE (0.2 U/ml) and aminoacylase (172 kU/ml) incubated with 3HB-GGG (3.4 mg/ml) at 37 degrees C for 30 min-the Gly-Gly and Gly cleaved from 3HB-GGG by enzymes was able to be identified, affirming the feasibility of substituting 3HB-GGG for the conventional substrate HHL. | 3-Hydroxybutyric Acid | angiotensin I converting enzyme | Homo sapiens |