Pub. Date : 2007 Mar
PMID : 17383430
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. | Proline | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | Homo sapiens |
| 2 | Hepatitis B virus (HBV) is the most common etiologic agent in HCC, and its encoded X-protein (HBx) is oncogenic and possesses a serine-proline motif that may bind Pin1. | Proline | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | Homo sapiens |
| 3 | RESULTS: We showed preferential Pin1 overexpression in HBV-related tumors and confirmed the interaction between Pin1 and HBx at the specific serine-proline motif. | Proline | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | Homo sapiens |