Pub. Date : 2007 Jun 1
PMID : 17382909
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Reactivators (oximes) of inhibited AChE are a mainstay of treatment. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | However, human AChE inhibited by certain OP, e.g. the phosphoramidates tabun and fenamiphos, is rather resistant towards reactivation by oximes while AChE inhibited by others, e.g. the phosphoramidate methamidophos is easily reactivated by oximes. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | However, human AChE inhibited by certain OP, e.g. the phosphoramidates tabun and fenamiphos, is rather resistant towards reactivation by oximes while AChE inhibited by others, e.g. the phosphoramidate methamidophos is easily reactivated by oximes. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | A clear structure-activity relationship of aging, spontaneous and oxime-induced reactivation kinetics could be determined with AChE inhibited by N-monoalkyl tabun analogues depending on the chain length of the N-alkyl residue. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |