Title : A novel anticancer agent, icaritin, induced cell growth inhibition, G1 arrest and mitochondrial transmembrane potential drop in human prostate carcinoma PC-3 cells.

Pub. Date : 2007 Jun 14

PMID : 17382317






1 Functional Relationships(s)
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1 Consistently with G(1) arrest, icaritin increased protein expressions of pRb, p27(Kip1) and p16(Ink4a), while showed decrease in phosphorylated pRb, Cyclin D1 and CDK4. icaritin cyclin D1 Homo sapiens