Title : Dysregulation of HER2/HER3 signaling axis in Epstein-Barr virus-infected breast carcinoma cells.

Pub. Date : 2007 Jun

PMID : 17376931






2 Functional Relationships(s)
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1 The increased colony formation capacity in soft agar was associated with increased expression and activation of HER2/HER3 signaling cascades, as evidenced by the findings that the treatment of HER2 antibody trastuzumab (Herceptin), phosphatidylinositol 3-kinase inhibitor, or MEK inhibitor completely abolished the tumorigenic capacity. Agar erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 The increased colony formation capacity in soft agar was associated with increased expression and activation of HER2/HER3 signaling cascades, as evidenced by the findings that the treatment of HER2 antibody trastuzumab (Herceptin), phosphatidylinositol 3-kinase inhibitor, or MEK inhibitor completely abolished the tumorigenic capacity. Agar erb-b2 receptor tyrosine kinase 2 Homo sapiens