Title : Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells.

Pub. Date : 2008 Apr

PMID : 17376583






2 Functional Relationships(s)
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1 Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells. trichostatin A H3 histone pseudogene 16 Homo sapiens
2 OBJECTIVE: Following our observation that histone deacetylase inhibitors (HDACIs) trichostatin A (TSA) and valproic acid (VPA) can suppress proliferation of endometrial stromal cells, we sought to determine whether TSA and VPA do so by inducing cell cycle arrest and p21 expression. trichostatin A H3 histone pseudogene 16 Homo sapiens