Title : Does metronidazole interact with CYP3A substrates by inhibiting their metabolism through this metabolic pathway? Or should other mechanisms be considered?

Pub. Date : 2007 Apr

PMID : 17374625






1 Functional Relationships(s)
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1 DATA SYNTHESIS: Elevated plasma concentrations and toxicities have been reported for a number of CYP3A substrates including amiodarone, carbamazepine, quinidine, tacrolimus, and cyclosporine when administered with metronidazole. Cyclosporine cytochrome P450 family 3 subfamily A member 4 Homo sapiens