Title : Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat.

Pub. Date : 2007 May 22

PMID : 17374466






3 Functional Relationships(s)
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1 Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat. Monocrotaline RB transcriptional corepressor 1 Rattus norvegicus
2 This study was to investigate the potential effect of Rb1 on right ventricular hypertrophy (RVH) induced by monocrotaline (MCT) and its possible influence on calcineurin (CaN) signal trasnsduction pathway. Monocrotaline RB transcriptional corepressor 1 Rattus norvegicus
3 MCT-treated animals were administered with Rb1 (10 and 40 mg /kg) from day 1 to day 14 (preventive administration) or from day 15 to day 28 (therapeutic administration), or with vehicle as corresponding controls. Monocrotaline RB transcriptional corepressor 1 Rattus norvegicus