Pub. Date : 1992 Mar 1
PMID : 1737390
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TPA induced rapid translocation of the PKC-alpha isozyme and PKC activity to the membrane fraction of MCF-7 cells. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |
| 2 | TPA induced rapid translocation of the PKC-alpha isozyme and PKC activity to the membrane fraction of MCF-7 cells. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |
| 3 | Similar effects on PKC-alpha isozyme and PKC activity were seen in a second cell line whose growth was inhibited by TPA but not by bryostatin 1, MDA-MB-468. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |
| 4 | Similar effects on PKC-alpha isozyme and PKC activity were seen in a second cell line whose growth was inhibited by TPA but not by bryostatin 1, MDA-MB-468. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |
| 5 | Thus, differential actions of bryostatin 1 and TPA on PKC activity and alpha-isoform level in the membrane-associated fraction of MCF-7 and MDA-MB-468 cells may account for the divergent effects of these two agents on cell growth and morphology. | Tetradecanoylphorbol Acetate | protein kinase C alpha | Homo sapiens |