Title : Regulation of p53 nuclear export through sequential changes in conformation and ubiquitination.

Pub. Date : 2007 May 11

PMID : 17371868






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mutant p53 ubiquitination occurred at lysines in both the DNA-binding domain (DBD) and C terminus. Lysine tumor protein p53 Homo sapiens
2 Interestingly, Lys to Arg mutations that inhibited ubiquitination restored nuclear localization to mutant p53 but had no apparent effect on p53 conformation. Lysine tumor protein p53 Homo sapiens