Title : Nicotine promotes colon tumor growth and angiogenesis through beta-adrenergic activation.

Pub. Date : 2007 Jun

PMID : 17369603






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 beta-Adrenoceptors, cyclooxygenase-2 (COX-2), prostaglandin E(2) (PGE(2)), and vascular endothelial growth factor (VEGF) in tumor tissues were also increased by nicotine. Nicotine prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Activation of beta-adrenoceptors and the subsequent stimulation of COX-2, PGE(2), and VEGF expression is perhaps an important mechanism in the tumorigenic action of nicotine on colon tumor growth. Nicotine prostaglandin-endoperoxide synthase 2 Homo sapiens