Title : Activation of the ER stress gene gadd153 by hepatitis C virus sensitizes cells to oxidant injury.

Pub. Date : 2007 Jun

PMID : 17368854






2 Functional Relationships(s)
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1 Importantly, we showed that, following H2O2 treatment, gadd153 gene reached higher levels of expression in replicon cells. Hydrogen Peroxide DNA damage inducible transcript 3 Homo sapiens
2 Treatment of replicon cells with a specific small interfering RNA, targeted to gadd153 gene, reduced basal expression of gadd153 and decreased cell death following H2O2. Hydrogen Peroxide DNA damage inducible transcript 3 Homo sapiens