Title : Protective effects of Tacrolimus, a calcineurin inhibitor, in experimental periodontitis in rats.

Pub. Date : 2007 Sep

PMID : 17367747






2 Functional Relationships(s)
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1 More specifically, Tacrolimus suppressed the expression of serum interleukin (IL-1beta), tumour necrosis factor (TNF-alpha), IL-6, airpouch exudate PGE(2) and leukocytosis usually observed after the induction of periodontitis. Tacrolimus tumor necrosis factor Rattus norvegicus
2 Tacrolimus treatment in periodontitis-induced rats conferred protection against the inflammation-induced tissue and bone loss associated with periodontitis, through a mechanism involving IL-1beta, TNF-alpha and IL-6. Tacrolimus tumor necrosis factor Rattus norvegicus