Title : Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.

Pub. Date : 2007 Apr 10

PMID : 17367165






2 Functional Relationships(s)
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1 For the cPLA2alpha C2 domain, the target lipid phosphatidylcholine (PC) appears to be sufficient to drive membrane targeting to an internal membrane mimic at physiological Ca2+ levels, although the results do not rule out a second, unknown target molecule. Phosphatidylcholines phospholipase A2 group IVA Homo sapiens
2 For the cPLA2alpha C2 domain, the target lipid phosphatidylcholine (PC) appears to be sufficient to drive membrane targeting to an internal membrane mimic at physiological Ca2+ levels, although the results do not rule out a second, unknown target molecule. Phosphatidylcholines phospholipase A2 group IVA Homo sapiens