Title : Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle.

Pub. Date : 2007 Jun

PMID : 17363741






6 Functional Relationships(s)
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1 Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle. Glucose interleukin 6 Homo sapiens
2 Thus, IL-6 has also been suggested to promote insulin-mediated glucose utilization. Glucose interleukin 6 Homo sapiens
3 In this study, we determined the direct effects of IL-6 on glucose transport and signal transduction in human skeletal muscle. Glucose interleukin 6 Homo sapiens
4 We found that IL-6 increased glucose transport in human skeletal muscle 1.3-fold (P < 0.05). Glucose interleukin 6 Homo sapiens
5 IL-6 also increased skeletal muscle glucose incorporation into glycogen, as well as glucose oxidation (1.5- and 1.3-fold, respectively; P < 0.05). Glucose interleukin 6 Homo sapiens
6 In conclusion, acute IL-6 exposure increases glucose metabolism in resting human skeletal muscle. Glucose interleukin 6 Homo sapiens