Title : Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo.

Pub. Date : 2007 Jul 1

PMID : 17363730






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The TLR ligands lipopolysacharride (TLR4), zymosan (TLR2/6), and CpG oligonucleotide (TLR9) caused, in a complement-dependent manner, strikingly elevated plasma interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-alpha), and IL-1beta, and/or decreased plasma IL-12 levels in mice deficient in the membrane complement inhibitor decay-accelerating factor (DAF). Zymosan toll-like receptor 2 Mus musculus