Title : Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle.

Pub. Date : 2007 Jun

PMID : 17360977






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Tyrosine phosphorylation of IRS-1 initiates insulin signaling, whereas serine/threonine phosphorylation alters the ability of IRS-1 to transduce the insulin signal. Threonine insulin Homo sapiens
2 Serine/threonine phosphorylation of IRS-1 is affected by many factors, including insulin. Threonine insulin Homo sapiens
3 CONCLUSIONS: These results provide an assessment of IRS-1 phosphorylation in vivo and show that insulin has profound effects on IRS-1 serine/threonine phosphorylation in healthy humans. Threonine insulin Homo sapiens