Title : Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid.

Pub. Date : 2007 May

PMID : 17351657






1 Functional Relationships(s)
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1 KEY RESULTS: Dithiolethione derivatives of diclofenac, valproate, and sulindac inhibited endothelial cell proliferation and induced Ser(78) phosphorylation of hsp27, a known molecular target of anti-angiogenic signaling. Valproic Acid heat shock protein, alpha-crystallin-related, 1 Danio rerio