Title : Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates.

Pub. Date : 2007 May

PMID : 17350277






1 Functional Relationships(s)
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1 While we recently demonstrated that levodopa-induced dyskinesia results from increased dopamine D(1) receptor-mediated transmission, we also questioned the possible role of subcellular localization of D(1) and D(2) receptors in mediating these effects as we previously showed that D(1) receptors undergo differential trafficking in striatal neurons of non-dyskinetic PD patients. Levodopa dopamine receptor D1 Homo sapiens