Title : Rosiglitazone, a PPARgamma ligand, modulates signal transduction pathways during the development of acute TNBS-induced colitis in rats.

Pub. Date : 2007 May 21

PMID : 17343846






1 Functional Relationships(s)
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1 Inflammation following TNBS induction was characterized by increased colonic wall thickness, edema, diffuse inflammatory cells infiltration, necrosis reaching an ulcer index (UI) of 9.66+/-0.66 cm(2) and increased MPO activity and TNF-alpha colonic levels. Trinitrobenzenesulfonic Acid myeloperoxidase Rattus norvegicus