Pub. Date : 2007 Apr
PMID : 17339833
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer. | Biguanides | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 2 | This resulted in reduced phosphorylation of AMPK, establishing a link between biguanide-induced mitochondrial inhibition and AMPK activation. | Biguanides | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 3 | This resulted in reduced phosphorylation of AMPK, establishing a link between biguanide-induced mitochondrial inhibition and AMPK activation. | Biguanides | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |