Title : Calcium-activated butyrylcholinesterase in human skin protects acetylcholinesterase against suicide inhibition by neurotoxic organophosphates.

Pub. Date : 2007 Apr 20

PMID : 17335779






1 Functional Relationships(s)
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1 Considering the large size of the human skin with 1.8m(2) surface area with its calcium gradient in the 10(-3)M range, our results implicate calcium-activated BuchE as a major protective mechanism against suicide inhibition of AchE by organophosphates in this non-neuronal tissue. Calcium acetylcholinesterase (Cartwright blood group) Homo sapiens