Pub. Date : 1992
PMID : 1733553
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Beta-carotene and/or vitamin E as modulators of alkylating agents in SCC-25 human squamous carcinoma cells. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 2 | We report on the cytotoxicity of beta-carotene, vitamin E, and the combination of beta-carotene and vitamin E in human SCC-25 squamous carcinoma cells under various environmental conditions found in solid tumor masses. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 3 | We report on the cytotoxicity of beta-carotene, vitamin E, and the combination of beta-carotene and vitamin E in human SCC-25 squamous carcinoma cells under various environmental conditions found in solid tumor masses. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 4 | Beta-Carotene was an effective modulator of cisplatin (CDDP) cytotoxicity toward SCC-25 cells, whereas vitamin E was not. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 5 | Both beta-carotene and vitamin E were effective modulators of melphalan cytotoxicity toward SCC-25 cells. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 6 | Treatment of SCC-25 cells with beta-carotene (70 microM, 2h) resulted in a reduction in superoxide dismutase activity, in glutathione-S-transferase activity, and in nonprotein sulfhydryl levels in the cells. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 7 | Exposure to vitamin E or to a combination of beta-carotene and vitamin E increased the glutathione-S-transferase activity in SCC-25 cells by 40%-45% over the control value. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 8 | Treatment with beta-carotene, vitamin E, or canthaxanthin reduced the incorporation of [3H]-thymidine into SCC-25 cells but not that into normal human keratinocytes. | beta Carotene | serpin family B member 3 | Homo sapiens |
| 9 | The most marked reduction in [3H]-thymidine incorporation into SCC-25 cells occurred following treatment with the combination of beta-carotene and melphalan. | beta Carotene | serpin family B member 3 | Homo sapiens |