Pub. Date : 2007 Apr
PMID : 17320939
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity. | Carbamazepine | CD4 molecule | Homo sapiens |
| 2 | OBJECTIVES: The aim of these studies was to generate and characterize CD4(+), CD8(+), and CD4(+)CD8(+) T cells in patients with carbamazepine hypersensitivity. | Carbamazepine | CD4 molecule | Homo sapiens |
| 3 | OBJECTIVES: The aim of these studies was to generate and characterize CD4(+), CD8(+), and CD4(+)CD8(+) T cells in patients with carbamazepine hypersensitivity. | Carbamazepine | CD4 molecule | Homo sapiens |
| 4 | CD4(+) T-cell clones proliferated vigorously with carbamazepine associated with MHC class II but exhibited little cytotoxic activity. | Carbamazepine | CD4 molecule | Homo sapiens |
| 5 | Carbamazepine was presented to CD4(+), CD8(+), and CD4(+)CD8(+) T cells in the absence of antigen processing. | Carbamazepine | CD4 molecule | Homo sapiens |
| 6 | Carbamazepine was presented to CD4(+), CD8(+), and CD4(+)CD8(+) T cells in the absence of antigen processing. | Carbamazepine | CD4 molecule | Homo sapiens |
| 7 | CONCLUSION: Carbamazepine-specific CD4(+), CD8(+), and CD4(+)CD8(+) T cells exist in the peripheral circulation of hypersensitive patients, often many years after the resolution of clinical manifestations. | Carbamazepine | CD4 molecule | Homo sapiens |
| 8 | CLINICAL IMPLICATIONS: Carbamazepine-specific CD4(+), CD8(+), and CD4(+)CD8(+) T cells displaying different effector functions and homing characteristics persist in hypersensitive patients" blood for many years after resolution of clinical symptoms. | Carbamazepine | CD4 molecule | Homo sapiens |