Title : Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant.

Pub. Date : 2007 Feb 15

PMID : 17317846






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The results provide clinical implications that therapeutic targeting at the BRAF/MEK/MAP kinase pathway may be a good approach in restoring thyroid gene expression for effective radioiodine therapy for BRAF mutation-harboring PTC. Iodine-131 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens
2 The results provide clinical implications that therapeutic targeting at the BRAF/MEK/MAP kinase pathway may be a good approach in restoring thyroid gene expression for effective radioiodine therapy for BRAF mutation-harboring PTC. Iodine-131 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens