Title : Bidirectional shifts of TRPM8 channel gating by temperature and chemical agents modulate the cold sensitivity of mammalian thermoreceptors.

Pub. Date : 2007 May 15

PMID : 17317754






1 Functional Relationships(s)
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1 We show that cold-evoked TRPM8 responses are effectively suppressed by inhibitor compounds SKF96365, 4-(3-chloro-pyridin-2-yl)-piperazine-1-carboxylic acid (4-tert-butyl-phenyl)-amide (BCTC) and 1,10-phenanthroline. 1,10-phenanthroline transient receptor potential cation channel subfamily M member 8 Homo sapiens