Title : 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.

Pub. Date : 2007 Feb

PMID : 17308059






1 Functional Relationships(s)
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1 ROS-quenching agents, inhibition of mitochondrial function, expression of dominant-negative thioredoxin reductase, or expression of dominant-negative apoptosis signaling kinase 1 suppressed JNK1/2 and p38 MAPK activation and reduced cell killing after 17AAG and DCA exposure. Reactive Oxygen Species mitogen-activated protein kinase 3 Homo sapiens