Title : Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol.

Pub. Date : 2007 Aug

PMID : 17295091






3 Functional Relationships(s)
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1 Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol. tert-Butylhydroperoxide heme oxygenase 1 Homo sapiens
2 In the present work we found an increased mRNA and protein level of interleukin-11 and heme oxygenase-1 in premature senescence of WI-38 human diploid foetal lung fibroblasts induced by both tert-butylhydroperoxide and ethanol. tert-Butylhydroperoxide heme oxygenase 1 Homo sapiens
3 We tested whether interleukin-11 and heme oxygenase-1 could protect against tert-butylhydroperoxide- or ethanol-induced premature senescence when stable overexpression was established using a retroviral vector-based transduction. tert-Butylhydroperoxide heme oxygenase 1 Homo sapiens